HOW TO TAKE
OXBRYTA

TULLY & HAJAR

Sisters, artists, and actual Oxbryta patients

ONCE-DAILY OXBRYTA COMES IN DIFFERENT DOSAGE FORMS

  • Oxbryta 300 mg Tablets for Oral Suspension for patients ages 4 years and older, based on patient’s weight and ability to swallow tablets, which should first be mixed in a room temperature clear drink such as drinking water, clear soda, apple juice, clear electrolyte drinks, clear flavored drinks, or clear sports drink before taking. Do not swallow whole, cut, crush, or chew the tablets for oral suspension.

  • Oxbryta 300 mg Tablets for patients ages 4 to less than 12 years, based on weight and ability to swallow tablets, which are swallowed whole. Do not cut, crush, or chew the tablets.

  • Oxbryta 500 mg Tablets for patients ages 12 and up, as well as patients ages 4 to less than 12 who weigh 88 lbs (40 kg) or more,* which are swallowed whole. Do not cut, crush, or chew the tablets.

Based on patient's ability to swallow tablets.

Remember, do not change your dose or stop taking Oxbryta unless your healthcare provider tells you to. Please see Patient Prescribing Information and Instructions for Use for complete information on Dosage and Administration.

OXBRYTA 300 MG TABLETS FOR ORAL SUSPENSION

Oxbryta 300 mg Tablets for Oral Suspension bottle

HOW TO PREPARE

Before you get started, have the following ready:

How To Prepare spoon icon

Teaspoon

How To Prepare small cup (or glass) icon

Small cup

How To Prepare water or other clear drink icon

Room temperature clear drink (For example: drinking water, clear soda, apple juice, clear electrolyte drinks, clear flavored drinks, or clear sports drinks)

How To Prepare Oxbryta 300 mg  Tablets for Oral Suspension icon

The prescribed number of Oxbryta 300 mg Tablets for Oral Suspension, which are light yellow, round shaped, and marked with “300 D” on one side


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See how Dr Scott prepares Oxbryta 300 mg Tablets for Oral Suspension in this step-by-step video guide.


STEPS FOR PREPARING AND TAKING OR GIVING OXBRYTA 300 MG TABLETS FOR ORAL SUSPENSION

POUR CLEAR DRINK

Visually inspect the pills to ensure it is the correct medication.

Be sure your hands are clean and dry, then pour room temperature clear drink in the cup. Use the table below as a guide for the minimum amount of liquid needed for the prescribed dose. You may add more clear drink if needed to mix the tablets.

Pour clear drink in bottle
NUMBER OF OXBRYTA 300 MG TABLETS
FOR ORAL SUSPENSION
AMOUNT OF CLEAR DRINK
11 tsp (5 mL)
22 tsp (10 mL)
33 tsp (15 mL)
44 tsp (20 mL)
55 tsp (25 mL)
77 tsp (35 mL)
88 tsp (40 mL)

ADD TABLET(S)

Add the prescribed number of Oxbryta 300 mg Tablet(s) for Oral Suspension to the cup.

  • Do not swallow whole, cut, crush, or chew the tablets for oral suspension

Hand dropping tablet in glass

SWIRL & WAIT

Swirl the cup until the tablet(s) break down in the drink. Take care not to spill. The tablet(s) will not completely dissolve. You will still see small tablet clumps in the mixture.

  • If you spill any medicine, clean up the spill. Throw away the rest of the prepared medicine and start again

Wait for 1 to 5 minutes before taking or giving the dose.

Hand swirling cup and waiting

SWIRL & DRINK

Swirl the cup again. Take care not to spill. Drink immediately.

  • If giving to a child, make sure that the child is upright. Give all the prepared medicine to the child immediately

Hand swirling cup and child drinking

ADD MORE LIQUID & REPEAT

Add 1 or 2 more teaspoons of room temperature clear drink to the cup. This is to mix the leftover medicine and to make sure the full dose is taken. Swirl the cup until all the leftover medicine is mixed, and drink immediately. Repeat this step until all the medicine is taken.

  • After taking all the medicine, you may drink any type of drink

  • Be sure to wash the spoon and cup with warm water and soap

Adding more liquid and swirling

Please see Instructions for Use for complete information.

OXBRYTA  300 MG  TABLETS
FOR ORAL SUSPENSION
Oxbryta 300 mg Tablets for Oral Suspension Dosing Guide

Oxbryta 300 mg Tablets for Oral Suspension Dosing Card

Information about dosing and taking Oxbryta 300 mg Tablets for Oral Suspension.

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"When I grow up, I want to be an actor and an artist."

– HAJAR

Actual Oxbryta patient

HAJAR

Actual Oxbryta patient

OXBRYTA 300 MG TABLETS

STEPS FOR TAKING OXBRYTA 300 MG TABLETS

Visually inspect the pills to ensure it is the correct medication. The Oxbryta 300 mg Tablets are film-coated, light purple to purple, oval shaped, and marked with “G 300” on one side.

Swallow tablets whole once a day or exactly as your healthcare provider tells you.

  • Do not cut, crush, or chew the tablets

RECOMMENDED DOSENUMBER OF OXBRYTA 300 MG TABLETS
300 mg1
600 mg2
900 mg3
1,200 mg4
1,500 mg5
2,100 mg7
2,400 mg8

Take with or without food.

Oxbryta (voxelotor) 300 mg Tablets bottle

STEPS FOR TAKING OXBRYTA 300 MG TABLETS

OXBRYTA  300 MG  TABLETS
Oxbryta (voxelotor) 300 mg Tablets Dosing Guide

Oxbryta 300 mg Tablets Dosing Card

Information about dosing and taking Oxbryta 300 mg Tablets.

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OXBRYTA 500 MG TABLETS

STEPS FOR TAKING OXBRYTA 500 MG TABLETS

Visually inspect the pills to ensure it is the correct medication. The Oxbryta 500 mg Tablets are film-coated, light yellow, oval shaped and marked with “GBT 500” on one side.

Swallow tablets whole once a day or exactly as your healthcare provider tells you.

  • Do not cut, crush, or chew the tablets

RECOMMENDED DOSENUMBER OF OXBRYTA 500 MG TABLETS
1,000 mg2
1,500 mg3
2,000 mg4
2,500 mg5

Take with or without food.

Oxbryta (voxelotor) 500 mg Tablets bottle

STEPS FOR TAKING OXBRYTA 500 MG TABLETS

OXBRYTA  500 MG  TABLETS
Oxbryta (voxelotor) 500 mg Tablets Dosing Guide

Oxbryta 500 mg Tablets Dosing Card

Information about dosing and taking Oxbryta 500 mg Tablets.

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IMPORTANT INFORMATION ABOUT TAKING OXBRYTA

Keep in mind the tips below when taking either Oxbryta 500 mg Tablets or Oxbryta 300 mg Tablets for Oral Suspension.

  • Take Oxbryta exactly as your healthcare provider tells you
  • Do not change your dose or stop taking Oxbryta unless your healthcare provider tells you to
  • Take the full prescribed dose of Oxbryta 1 time each day
  • Your healthcare provider may change your dose if needed
  • Your healthcare provider may also prescribe a medicine called hydroxyurea during treatment with Oxbryta
  • Take Oxbryta with or without food
  • If you miss a dose of Oxbryta or do not take the entire dose of Oxbryta, skip that dose and return to your normal dosing schedule the next day
  • Do not take St. John’s wort during treatment with Oxbryta

For full information on how you should take Oxbryta, please see the Patient Prescribing Information and Instructions for Use. If you have any questions, please talk to your healthcare provider.

HOW TO STORE OXBRYTA

  • Store Oxbryta at 68°F to 86°F (20°C to 30°C)

  • Oxbryta comes in a child-resistant package

  • The Oxbryta 300 mg Tablets bottle and Oxbryta 500 mg Tablets bottle each contain a desiccant to help keep your medicine dry (protect it from moisture) and a polyester coil. Do not eat

  • The Oxbryta 300 mg Tablets for Oral Suspension bottle contains a polyester coil. Do not eat

Keep Oxbryta and all medicines out of the reach of children.